Welcome to the Z. The swap you're suggesting is common, but takes a lot of experience and know-how. Sometimes it's best to buy a donor vehicle with the drivetrain you want. The stock axles will handle moderate driving until you were able to upgrade them. The GM 5.3L and 6.0L are common swaps. There are companies offering motor mounts, engine computers, and wiring harnesses to make install a lot easier. 4L60e or 4L80e would be good transmission choices.